What is the SIG for Narcan nasal spray 4 mg?

The SIG, or instructions for use, for Narcan nasal spray 4 mg is best described as administering a single spray intranasally. This option correctly reflects the recommended and indicated method of administration for Narcan, which is designed for rapid delivery of naloxone to reverse opioid overdoses.

In clinical practice and according to guidelines, Narcan nasal spray is designed for easy use, requiring only a single spray into one of the patient's nostrils. This method allows for quick absorption through the nasal membranes, facilitating rapid reversal of opioid effects. It's a life-saving intervention that can be performed by bystanders or non-medical personnel, which underscores the importance of straightforward and accessible administration instructions.

Other options do not accurately represent the proper use of Narcan. For instance, administering multiple sprays in quick succession could lead to confusion and is not the recommended approach. Injecting intramuscularly is unsuitable here, as Narcan is specifically formulated for intranasal delivery in its spray form. Likewise, mixing Narcan with water before use would not only be unnecessary but could also compromise the effectiveness of the medication.

Thus, employing the intranasal route as indicated ensures patients receive the full benefit of the medication in a straightforward user-friendly manner.